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MicroRNA-181 contributes to downregulation of SAMHD1 expression in CD4+ T-cells derived from Sèzary syndrome patients

Sézary syndrome (SS) is a rare subtype of cutaneous T-cell lymphoma (CTCL) that is characterized by aggressive spread of neoplastic CD4+ T-cells from the skin into the bloodstream with metastasis to visceral organs. The deoxynucleoside triphosphohydrolase SAMHD1 is highly expressed in normal CD4+ T-...

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Publicado en:Leuk Res
Main Authors: Kohnken, Rebecca, Kodigepalli, Karthik M., Mishra, Anjali, Porcu, Pierluigi, Wu, Li
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5195900/
https://ncbi.nlm.nih.gov/pubmed/27889686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2016.11.010
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