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Specific In Vivo Labeling of Tyrosinated α-Tubulin and Measurement of Microtubule Dynamics Using a GFP Tagged, Cytoplasmically Expressed Recombinant Antibody

GFP-tagged proteins are used extensively as biosensors for protein localization and function, but the GFP moiety can interfere with protein properties. An alternative is to indirectly label proteins using intracellular recombinant antibodies (scFvs), but most antibody fragments are insoluble in the...

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Hlavní autoři: Cassimeris, Lynne, Guglielmi, Laurence, Denis, Vincent, Larroque, Christian, Martineau, Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610906/
https://ncbi.nlm.nih.gov/pubmed/23555790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059812
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