Prophylaxis and Treatment of Alzheimer's Disease by Delivery of an Adeno-Associated Virus Encoding a Monoclonal Antibody Targeting the Amyloid Beta Protein

We previously reported on a monoclonal antibody (mAb) that targeted amyloid beta (Aß) protein. Repeated injection of that mAb reduced the accumulation of Aß protein in the brain of human Aß transgenic mice (Tg2576). In the present study, cDNA encoding the heavy and light chains of this mAb were subc...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Shimada, Masaru, Abe, Shinya, Takahashi, Toru, Shiozaki, Kazumasa, Okuda, Mitsue, Mizukami, Hiroaki, Klinman, Dennis M., Ozawa, Keiya, Okuda, Kenji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610755/
https://ncbi.nlm.nih.gov/pubmed/23555563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057606
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker