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Adeno-associated virus vector-mediated production of hepatocyte growth factor attenuates liver fibrosis in mice
PURPOSE: Adeno-associated virus (AAV) vectors can achieve long-term gene expression and are now feasible for use in human gene therapy. We constructed hepatocyte growth factor (HGF) expressing AAV (AAV5-HGF) and examined its effect in two mouse hepatic fibrosis models. METHODS: A model of hepatic fi...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716862/ https://ncbi.nlm.nih.gov/pubmed/19669282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-007-9042-1 |
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