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FAK Inhibition Decreases Hepatoblastoma Survival Both In Vitro and In Vivo

Hepatoblastoma is the most frequently diagnosed liver tumor of childhood, and children with advanced, metastatic or relapsed disease have a disease-free survival rate under 50%. Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that is important in many facets of tumor development and pro...

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Bibliographic Details
Main Authors: Gillory, Lauren A, Stewart, Jerry E, Megison, Michael L, Nabers, Hugh C, Mroczek-Musulman, Elizabeth, Beierle, Elizabeth A
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610546/
https://ncbi.nlm.nih.gov/pubmed/23544173
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