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Inhibition of Focal Adhesion Kinase (FAK) Leads to Abrogation of the Malignant Phenotype in Aggressive Pediatric Renal Malignancies

Despite the tremendous advances in the treatment of childhood kidney tumors, there remain subsets of pediatric renal tumors that continue to pose a therapeutic challenge, mainly malignant rhabdoid kidney tumors and non-osseous renal Ewing sarcoma. Children with advanced, metastatic or relapsed disea...

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Detalhes bibliográficos
Main Authors: Megison, Michael L., Gillory, Lauren A., Stewart, Jerry E., Nabers, Hugh C., Mrozcek-Musulman, Elizabeth, Beierle, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989502/
https://ncbi.nlm.nih.gov/pubmed/24464916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0505
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