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FAK inhibition decreases cell invasion, migration and metastasis in MYCN amplified neuroblastoma
Neuroblastoma, the most common extracranial solid tumor of childhood, is responsible for over 15 % of pediatric cancer deaths. We have shown that neuroblastoma cell lines overexpress focal adhesion kinase (FAK), a non-receptor protein tyrosine kinase that controls a number of tumorigenic pathways. I...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625446/ https://ncbi.nlm.nih.gov/pubmed/23208732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-012-9560-7 |
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