The Presence of PIM3 Increases Hepatoblastoma Tumorigenesis and Tumor Initiating Cell Phenotype and is Associated with Decreased Patient Survival

PURPOSE: Hepatoblastoma is the most common primary liver cancer of childhood and has few prognostic indicators. We have previously shown that Proviral Integration site for Moloney murine leukemia virus (PIM3) kinase decreased hepatoblastoma tumorigenicity. We sought to determine the effect of PIM3 o...

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Detalhes bibliográficos
Publicado no:J Pediatr Surg
Main Authors: Stafman, Laura L, Waldrop, Mary G, Williams, Adele P, Aye, Jamie M, Stewart, Jerry E, Mroczek-Musulman, Elizabeth, Yoon, Karina J, Whelan, Kimberly, Beierle, Elizabeth A
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545248/
https://ncbi.nlm.nih.gov/pubmed/30898394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2019.02.029
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