Saikosaponin-d Enhances the Anticancer Potency of TNF-α via Overcoming Its Undesirable Response of Activating NF-Kappa B Signalling in Cancer Cells

Tumor necrosis factor-alpha (TNF-α) was reported as anticancer therapy due to its cytotoxic effect against an array of tumor cells. However, its undesirable responses of TNF-α on activating NF-κB signaling and pro-metastatic property limit its clinical application in treating cancers. Therefore, sen...

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Detalhes bibliográficos
Main Authors: Wong, Vincent Kam Wai, Zhang, Molly Miao, Zhou, Hua, Lam, Kelly Yin Ching, Chan, Po Ling, Law, Carmen Ka Man, Yue, Patrick Ying Kit, Liu, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610377/
https://ncbi.nlm.nih.gov/pubmed/23573150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/745295
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