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Apoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists

Various criteria are necessary to assess the efficacy and safety of biological medications in order to grant companies the right to register these medications with the appropriate bodies that regulate their sale. The imminent expiration of the patents on reference biological products which block the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Urbano, Paulo César Martins, Soccol, Vanete Thomaz, Azevedo, Valderilio Feijó
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124053/
https://ncbi.nlm.nih.gov/pubmed/25114503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S57253
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