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Apoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists

Various criteria are necessary to assess the efficacy and safety of biological medications in order to grant companies the right to register these medications with the appropriate bodies that regulate their sale. The imminent expiration of the patents on reference biological products which block the...

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Détails bibliographiques
Auteurs principaux: Urbano, Paulo César Martins, Soccol, Vanete Thomaz, Azevedo, Valderilio Feijó
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124053/
https://ncbi.nlm.nih.gov/pubmed/25114503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S57253
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