Apoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists

Various criteria are necessary to assess the efficacy and safety of biological medications in order to grant companies the right to register these medications with the appropriate bodies that regulate their sale. The imminent expiration of the patents on reference biological products which block the...

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Bibliographic Details
Main Authors: Urbano, Paulo César Martins, Soccol, Vanete Thomaz, Azevedo, Valderilio Feijó
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124053/
https://ncbi.nlm.nih.gov/pubmed/25114503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S57253
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