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Loss of NF-kappaB activity during cerebral ischemia and TNF cytotoxicity.

Recent evidence implicates tumor necrosis factor (TNF), a cytokine with both cytotoxic and cytoprotective activities, in the pathogenesis of cerebral ischemia. The development of TNF cytotoxicity is dependent upon the balance between the activities of intracellular signaling pathways that mediate ei...

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Bibliografiske detaljer
Main Authors: Botchkina, G. I., Geimonen, E., Bilof, M. L., Villarreal, O., Tracey, K. J.
Format: Artigo
Sprog:Inglês
Udgivet: The Feinstein Institute for Medical Research 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230435/
https://ncbi.nlm.nih.gov/pubmed/10415162
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