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Reduction of the Rate of Protein Translation in Patients with Myotonic Dystrophy 2

Myotonic dystrophy 2 (DM2) is an autosomal dominant, multisystem disease, which primarily affects skeletal muscle. DM2 is caused by CCTGn expansion in the intron 1 of the ZNF9 gene. Expression of the mutant CCUGn RNA changes RNA processing in patients with DM2; however, the role of ZNF9 protein in D...

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Bibliografiset tiedot
Päätekijät: Huichalaf, Claudia, Schoser, Benedikt, Schneider-Gold, Christiane, Jin, Bingwen, Sarkar, Partha, Timchenko, Lubov
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610333/
https://ncbi.nlm.nih.gov/pubmed/19605641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1983-09.2009
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