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Myotonic Dystrophies 1 and 2: Complex Diseases with Complex Mechanisms
Two multi-system disorders, Myotonic Dystrophies type 1 and type 2 (DM1 and DM2), are complex neuromuscular diseases caused by an accumulation of expanded, non-coding RNAs, containing repetitive CUG and CCUG elements. Similarities of these mutations suggest similar mechanisms for both diseases. The...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Bentham Science Publishers Ltd.
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874224/ https://ncbi.nlm.nih.gov/pubmed/20885816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920210790886844 |
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