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Molecular mechanisms of muscle atrophy in myotonic dystrophies
Myotonic dystrophy type 1 (DM1) and myotonic dystrophy type 2 (DM2) are multisystemic diseases that primarily affect skeletal muscle, causing myotonia, muscle atrophy, and muscle weakness. DM1 and DM2 pathologies are caused by expansion of CTG and CCTG repeats in non-coding regions of the genes enco...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3759660/ https://ncbi.nlm.nih.gov/pubmed/23796888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2013.06.010 |
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