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Molecular Basis for Impaired Muscle Differentiation in Myotonic Dystrophy

Differentiation of skeletal muscle is affected in myotonic dystrophy (DM) patients. Analysis of cultured myoblasts from DM patients shows that DM myoblasts lose the capability to withdraw from the cell cycle during differentiation. Our data demonstrate that the expression and activity of the protein...

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Detalhes bibliográficos
Main Authors: Timchenko, Nikolai A., Iakova, Polina, Cai, Zong-Jin, Smith, James R., Timchenko, Lubov T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99869/
https://ncbi.nlm.nih.gov/pubmed/11564876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.20.6927-6938.2001
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