A carregar...

Disturbance of DNA conformation by the binding of testosterone-based platinum drugs via groove-face and intercalative interactions: a molecular dynamics simulation study

BACKGROUND: To explore novel platinum-based anticancer agents that are distinct from the structure and interaction mode of the traditional cisplatin by forming the bifunctional intrastrand 1,2 GpG adduct, the monofunctional platinum + DNA adducts with extensive non-covalent interactions had been stu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cui, Shanshan, Wang, Yan, Chen, Guangju
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610147/
https://ncbi.nlm.nih.gov/pubmed/23517640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!