טוען...

Disturbance of DNA conformation by the binding of testosterone-based platinum drugs via groove-face and intercalative interactions: a molecular dynamics simulation study

BACKGROUND: To explore novel platinum-based anticancer agents that are distinct from the structure and interaction mode of the traditional cisplatin by forming the bifunctional intrastrand 1,2 GpG adduct, the monofunctional platinum + DNA adducts with extensive non-covalent interactions had been stu...

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מידע ביבליוגרפי
Main Authors: Cui, Shanshan, Wang, Yan, Chen, Guangju
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610147/
https://ncbi.nlm.nih.gov/pubmed/23517640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-4
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