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Mechanism for retardation of amyloid fibril formation by sugars in Vλ6 protein

Sugars, which function as osmolytes within cells, retard the amyloid fibril formation of the amyloidosis peptides and proteins. To examine the mechanism of this retardation in detail, we analyzed the effect of sugars (trehalose, sucrose, and glucose) on the polypeptide chains in 3Hmut Wil, which is...

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Autors principals: Abe, Masahiro, Abe, Yoshito, Ohkuri, Takatoshi, Mishima, Tomonori, Monji, Akira, Kanba, Shigenobu, Ueda, Tadashi
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610052/
https://ncbi.nlm.nih.gov/pubmed/23389799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2228
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