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Mechanism for retardation of amyloid fibril formation by sugars in Vλ6 protein

Sugars, which function as osmolytes within cells, retard the amyloid fibril formation of the amyloidosis peptides and proteins. To examine the mechanism of this retardation in detail, we analyzed the effect of sugars (trehalose, sucrose, and glucose) on the polypeptide chains in 3Hmut Wil, which is...

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Detalhes bibliográficos
Main Authors: Abe, Masahiro, Abe, Yoshito, Ohkuri, Takatoshi, Mishima, Tomonori, Monji, Akira, Kanba, Shigenobu, Ueda, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610052/
https://ncbi.nlm.nih.gov/pubmed/23389799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2228
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