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Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation
Metal ions have emerged to play a key role in the aggregation process of amyloid β (Aβ) peptide that is closely related to the pathogenesis of Alzheimer’s disease. A detailed understanding of the underlying mechanistic process of peptide–metal interactions, however, has been challenging to obtain. B...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418866/ https://ncbi.nlm.nih.gov/pubmed/25825723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421961112 |
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