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Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation

Metal ions have emerged to play a key role in the aggregation process of amyloid β (Aβ) peptide that is closely related to the pathogenesis of Alzheimer’s disease. A detailed understanding of the underlying mechanistic process of peptide–metal interactions, however, has been challenging to obtain. B...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Abelein, Axel, Gräslund, Astrid, Danielsson, Jens
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418866/
https://ncbi.nlm.nih.gov/pubmed/25825723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421961112
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