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Metal ion coordination delays amyloid-β peptide self-assembly by forming an aggregation–inert complex
A detailed understanding of the molecular pathways for amyloid-β (Aβ) peptide aggregation from monomers into amyloid fibrils, a hallmark of Alzheimer's disease, is crucial for the development of diagnostic and therapeutic strategies. We investigate the molecular details of peptide fibrillizatio...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7247290/ https://ncbi.nlm.nih.gov/pubmed/32241918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012738 |
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