Mercury and Alzheimer’s Disease: Hg(II) Ions Display Specific Binding to the Amyloid-β Peptide and Hinder Its Fibrillization

Brains and blood of Alzheimer’s disease (AD) patients have shown elevated mercury concentrations, but potential involvement of mercury exposure in AD pathogenesis has not been studied at the molecular level. The pathological hallmark of AD brains is deposition of amyloid plaques, consisting mainly o...

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Bibliografiske detaljer
Udgivet i:Biomolecules
Main Authors: Wallin, Cecilia, Friedemann, Merlin, Sholts, Sabrina B., Noormägi, Andra, Svantesson, Teodor, Jarvet, Jüri, Roos, Per M., Palumaa, Peep, Gräslund, Astrid, Wärmländer, Sebastian K. T. S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022868/
https://ncbi.nlm.nih.gov/pubmed/31892131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10010044
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