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Effect of methionine-35 oxidation on the aggregation of amyloid-β peptide

Aggregation of Aβ peptides into amyloid plaques is considered to trigger the Alzheimer’s disease (AD), however the mechanism behind the AD onset has remained elusive. It is assumed that the insoluble Aβ aggregates enhance oxidative stress (OS) by generating free radicals with the assistance of bound...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Friedemann, Merlin, Helk, Eneken, Tiiman, Ann, Zovo, Kairit, Palumaa, Peep, Tõugu, Vello
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668694/
https://ncbi.nlm.nih.gov/pubmed/29124171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2015.07.017
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