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In situ fibrillizing amyloid-beta 1-42 induces neurite degeneration and apoptosis of differentiated SH-SY5Y cells

The progression of Alzheimer’s disease is causatively linked to the accumulation of amyloid-β aggregates in the brain, however, it is not clear how the amyloid aggregates initiate the death of neuronal cells. The in vitro toxic effects of amyloid peptides are most commonly examined using the human n...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Krishtal, Jekaterina, Bragina, Olga, Metsla, Kristel, Palumaa, Peep, Tõugu, Vello
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655426/
https://ncbi.nlm.nih.gov/pubmed/29065138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186636
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