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Cellular Polyamines Promote Amyloid-Beta (Aβ) Peptide Fibrillation and Modulate the Aggregation Pathways
[Image: see text] The cellular polyamines spermine, spermidine, and their metabolic precursor putrescine, have long been associated with cell-growth, tumor-related gene regulations, and Alzheimer’s disease. Here, we show by in vitro spectroscopy and AFM imaging, that these molecules promote aggregat...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605822/ https://ncbi.nlm.nih.gov/pubmed/23509981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300170x |
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