TGFβ Receptor Signaling Is Essential for Inflammation-Induced but Not β-Cell Workload–Induced β-Cell Proliferation

Protection and restoration of a functional β-cell mass are fundamental strategies for prevention and treatment of diabetes. Consequently, knowledge of signals that determine the functional β-cell mass is of immense clinical relevance. Transforming growth factor β (TGFβ) superfamily signaling pathway...

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Bibliographic Details
Main Authors: Xiao, Xiangwei, Wiersch, John, El-Gohary, Yousef, Guo, Ping, Prasadan, Krishna, Paredes, Jose, Welsh, Carey, Shiota, Chiyo, Gittes, George K.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609557/
https://ncbi.nlm.nih.gov/pubmed/23248173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1428
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