No evidence for β cell neogenesis in murine adult pancreas

Whether facultative β cell progenitors exist in the adult pancreas is a major unsolved question. To date, lineage-tracing studies have provided conflicting results. To track β cell neogenesis in vivo, we generated transgenic mice that transiently coexpress mTomato and GFP in a time-sensitive, noncon...

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Библиографические подробности
Главные авторы: Xiao, Xiangwei, Chen, Zean, Shiota, Chiyo, Prasadan, Krishna, Guo, Ping, El-Gohary, Yousef, Paredes, Jose, Welsh, Carey, Wiersch, John, Gittes, George K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639750/
https://ncbi.nlm.nih.gov/pubmed/23619362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66323
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