A simplified purification method for AAV variant by polyethylene glycol aqueous two-phase partitioning

Adeno-Associated Virus (AAV) has been widely used for in vivo study and preclinical therapy due to its ability to mediate long-term transgene expression, its lack of pathogenicity and low immunogenicity. It has been found that AAV has more than ten serotypes, which each transfect certain types of ce...

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Autores principales: Guo, Ping, Xiao, Xiangwei, El-Gohary, Yousef, Paredes, Jose, Prasadan, Krishna, Shiota, Chiyo, Wiersch, John, Welsh, Carey, Gittes, George K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609617/
https://ncbi.nlm.nih.gov/pubmed/22992716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioe.22293
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