Rapid and simplified purification of recombinant adeno-associated virus

Preclinical gene therapy studies both in-vitro and in-vivo require high purity preparations of adeno-associated virus (AAV). Current methods for purification of AAV entail the use of centrifugation over either a CsCl or iodixanol gradient, or the use of chromatography. These methods can be cumbersom...

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Bibliografiske detaljer
Main Authors: Guo, Ping, El-Gohary, Yousef, Prasadan, Krishna, Shiota, Chiyo, Xiao, Xiangwei, Wiersch, John, Paredes, Jose, Tulachan, Sidhartha, Gittes, George K.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374034/
https://ncbi.nlm.nih.gov/pubmed/22561982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2012.04.004
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