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Dynamics of the DNA damage response: insights from live-cell imaging

All organisms have to safeguard the integrity of their genome to prevent malfunctioning and oncogenic transformation. Sophisticated DNA damage response mechanisms have evolved to detect and repair genomic lesions. With the emergence of live-cell microscopy of individual cells, we now begin to apprec...

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Detalhes bibliográficos
Main Authors: Karanam, Ketki, Loewer, Alexander, Lahav, Galit
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609438/
https://ncbi.nlm.nih.gov/pubmed/23292635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bfgp/els059
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