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Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid-S phase
DNA double strand breaks are repaired by two main pathways: non-homologous end joining (NHEJ) and homologous recombination (HR). The choice between these pathways depends on cell cycle phase; however the continuous effect of cell cycle on the balance between them is still unclear. We used live cell...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494418/ https://ncbi.nlm.nih.gov/pubmed/22841003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.052 |
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