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Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid-S phase

DNA double strand breaks are repaired by two main pathways: non-homologous end joining (NHEJ) and homologous recombination (HR). The choice between these pathways depends on cell cycle phase; however the continuous effect of cell cycle on the balance between them is still unclear. We used live cell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Karanam, Ketki, Kafri, Ran, Loewer, Alexander, Lahav, Galit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494418/
https://ncbi.nlm.nih.gov/pubmed/22841003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.052
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