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Homodimerization as a molecular switch between low and high efficiency PrP(C) cell surface delivery and neuroprotective activity

PrP(C) is associated with a variety of functions, and its ability to interact with a multitude of partners, including itself, may largely explain PrP multifunctionality and the lack of consensus on the genuine physiological function of the protein in vivo. In contrast, there is a consensus in the li...

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Detalhes bibliográficos
Main Authors: Béland, Maxime, Roucou, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609126/
https://ncbi.nlm.nih.gov/pubmed/23357826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.23583
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