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Single-molecule approaches to prion protein misfolding
The structural conversion of the prion protein PrP into a transmissible, misfolded form is the central element of prion disease, yet there is little consensus as to how it occurs. Key aspects of conversion into the diseased state remain unsettled, from details about the earliest stages of misfolding...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3609121/ https://ncbi.nlm.nih.gov/pubmed/23357831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.23303 |
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