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Single-molecule approaches to prion protein misfolding

The structural conversion of the prion protein PrP into a transmissible, misfolded form is the central element of prion disease, yet there is little consensus as to how it occurs. Key aspects of conversion into the diseased state remain unsettled, from details about the earliest stages of misfolding...

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Bibliografiske detaljer
Main Authors: Yu, Hao, Dee, Derek R., Woodside, Michael T.
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609121/
https://ncbi.nlm.nih.gov/pubmed/23357831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.23303
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