Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity

BACKGROUND: Adenosine triphosphate (ATP) is secreted from hepatocytes under physiological conditions and plays an important role in liver biology through the activation of P2 receptors. Conversely, higher extracellular ATP concentrations, as observed during necrosis, trigger inflammatory responses t...

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Detaylı Bibliyografya
Asıl Yazarlar: Amaral, Sylvia S, Oliveira, André G, Marques, Pedro E, Quintão, Jayane L D, Pires, Daniele A, Resende, Rodrigo R, Sousa, Bruna R, Melgaço, Juliana G, Pinto, Marcelo A, Russo, Remo C, Gomes, Ariane K C, Andrade, Lidia M, Zanin, Rafael F, Pereira, Rafaela V S, Bonorino, Cristina, Soriani, Frederico M, Lima, Cristiano X, Cara, Denise C, Teixeira, Mauro M, Leite, Maria F, Menezes, Gustavo B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608937/
https://ncbi.nlm.nih.gov/pubmed/23384127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-10
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