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Platelets mediate acetaminophen hepatotoxicity

In this issue of Blood, Miyakawa et al show that platelets and protease-activated receptor (PAR)-4 contribute to acetaminophen (APAP)-induced liver damage. Using various strategies in a mouse model of APAP overdose, the authors demonstrate that platelets participate in the progression of liver damag...

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Foilsithe in:Blood
Main Authors: Lam, Fong W., Rumbaut, Rolando E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600013/
https://ncbi.nlm.nih.gov/pubmed/26450954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-659516
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