Transferrin Receptor-Targeted Lipid Nanoparticles for Delivery of an Antisense Oligodeoxyribonucleotide against Bcl-2

Antisense oligonucleotide G3139-mediated down-regulation of Bcl-2 is a potential strategy for overcoming chemoresistance in leukemia. However, the limited efficacy shown in recent clinical trials calls attention to the need for further development of novel and more efficient delivery systems. In ord...

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Main Authors: Yang, Xiaojuan, Koh, Chee Guan, Liu, Shujun, Pan, Xiaogang, Santhanam, Ramasamy, Yu, Bo, Peng, Yong, Pang, Jiuxia, Golan, Sharon, Talmon, Yeshayahu, Jin, Yan, Muthusamy, Natarajan, Byrd, John C., Chan, Kenneth K., Lee, L. James, Marcucci, Guido, Lee, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608852/
https://ncbi.nlm.nih.gov/pubmed/19183107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp800149s
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