Transferrin Receptor-Targeted Lipid Nanoparticles for Delivery of an Antisense Oligodeoxyribonucleotide against Bcl-2

Antisense oligonucleotide G3139-mediated down-regulation of Bcl-2 is a potential strategy for overcoming chemoresistance in leukemia. However, the limited efficacy shown in recent clinical trials calls attention to the need for further development of novel and more efficient delivery systems. In ord...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Xiaojuan, Koh, Chee Guan, Liu, Shujun, Pan, Xiaogang, Santhanam, Ramasamy, Yu, Bo, Peng, Yong, Pang, Jiuxia, Golan, Sharon, Talmon, Yeshayahu, Jin, Yan, Muthusamy, Natarajan, Byrd, John C., Chan, Kenneth K., Lee, L. James, Marcucci, Guido, Lee, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608852/
https://ncbi.nlm.nih.gov/pubmed/19183107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp800149s
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