A Systematic In Silico Search for Target Similarity Identifies Several Approved Drugs with Potential Activity against the Plasmodium falciparum Apicoplast

Most of the drugs in use against Plasmodium falciparum share similar modes of action and, consequently, there is a need to identify alternative potential drug targets. Here, we focus on the apicoplast, a malarial plastid-like organelle of algal source which evolved through secondary endosymbiosis. W...

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Detaylı Bibliyografya
Asıl Yazarlar: Bispo, Nadlla Alves, Culleton, Richard, Silva, Lourival Almeida, Cravo, Pedro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608639/
https://ncbi.nlm.nih.gov/pubmed/23555651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059288
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