Target-similarity search using Plasmodium falciparum proteome identifies approved drugs with anti-malarial activity and their possible targets

Malaria causes about half a million deaths annually, with Plasmodium falciparum being responsible for 90% of all the cases. Recent reports on artemisinin resistance in Southeast Asia warrant urgent discovery of novel drugs for the treatment of malaria. However, most bioactive compounds fail to progr...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Mogire, Reagan M., Akala, Hoseah M., Macharia, Rosaline W., Juma, Dennis W., Cheruiyot, Agnes C., Andagalu, Ben, Brown, Mathew L., El-Shemy, Hany A., Nyanjom, Steven G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663372/
https://ncbi.nlm.nih.gov/pubmed/29088219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186364
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items