The Plasmodium falciparum cytoplasmic translation apparatus: a promising therapeutic target not yet exploited by clinically approved anti-malarials

BACKGROUND: The continued spectre of resistance to existing anti-malarials necessitates the pursuit of novel targets and mechanisms of action for drug development. One class of promising targets consists of the 80S ribosome and its associated components comprising the parasite translational apparatu...

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Bibliographic Details
Published in:Malar J
Main Authors: Sheridan, Christine Moore, Garcia, Valentina E., Ahyong, Vida, DeRisi, Joseph L.
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6292128/
https://ncbi.nlm.nih.gov/pubmed/30541569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-018-2616-7
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