Identification of Plasmodium falciparum specific translation inhibitors from the MMV Malaria Box using a high throughput in vitro translation screen

BACKGROUND: A major goal in the search for new anti-malarial compounds is to identify new mechanisms of action or new molecular targets. While cell-based, growth inhibition-based screening have enjoyed tremendous success, an alternative approach is to specifically assay a given pathway or essential...

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Bibliographische Detailangaben
Veröffentlicht in:Malar J
Hauptverfasser: Ahyong, Vida, Sheridan, Christine M., Leon, Kristoffer E., Witchley, Jessica N., Diep, Jonathan, DeRisi, Joseph L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794828/
https://ncbi.nlm.nih.gov/pubmed/26987601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1231-8
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