Evaluation of In Vitro Cross-Reactivity to Avian H5N1 and Pandemic H1N1 2009 Influenza Following Prime Boost Regimens of Seasonal Influenza Vaccination in Healthy Human Subjects: A Randomised Trial

INTRODUCTION: Recent studies have demonstrated that inactivated seasonal influenza vaccines (IIV) may elicit production of heterosubtypic antibodies, which can neutralize avian H5N1 virus in a small proportion of subjects. We hypothesized that prime boost regimens of live and inactivated trivalent s...

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Autori principali: Bethell, Delia, Saunders, David, Jongkaewwattana, Anan, Kramyu, Jarin, Thitithayanont, Arunee, Wiboon-ut, Suwimon, Yongvanitchit, Kosol, Limsalakpetch, Amporn, Kum-Arb, Utaiwan, Uthaimongkol, Nichapat, Garcia, Jean Michel, Timmermans, Ans E., Peiris, Malik, Thomas, Stephen, Engering, Anneke, Jarman, Richard G., Mongkolsirichaikul, Duangrat, Mason, Carl, Khemnu, Nuanpan, Tyner, Stuart D., Fukuda, Mark M., Walsh, Douglas S., Pichyangkul, Sathit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608534/
https://ncbi.nlm.nih.gov/pubmed/23555741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059674
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