Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver

Whole malaria sporozoite vaccine regimens are promising new strategies, and some candidates have demonstrated high rates of durable clinical protection associated with memory T cell responses. Little is known about the anatomical distribution of memory T cells following whole sporozoite vaccines, an...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pichyangkul, Sathit, Spring, Michele D., Yongvanitchit, Kosol, Kum-Arb, Utaiwan, Limsalakpetch, Amporn, Im-Erbsin, Rawiwan, Ubalee, Ratawan, Vanachayangkul, Pattaraporn, Remarque, Edmond J., Angov, Evelina, Smith, Philip L., Saunders, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5300246/
https://ncbi.nlm.nih.gov/pubmed/28182750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171826
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