Antiviral immune responses in H5N1-infected human lung tissue and possible mechanisms underlying the hyperproduction of interferon-inducible protein IP-10

Information on the immune response against H5N1 within the lung is lacking. Here we describe the sustained antiviral immune responses, as indicated by the expression of MxA protein and IFN-α mRNA, in autopsy lung tissue from an H5N1-infected patient. H5N1 infection of primary bronchial/tracheal epit...

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Main Authors: Thitithanyanont, Arunee, Engering, Anneke, Uiprasertkul, Monkol, Ekchariyawat, Peeraya, Wiboon-ut, Suwimon, Kraivong, Romchat, Limsalakpetch, Amporn, Kum-Arb, Utaiwan, Yongvanitchit, Kosol, Sa-Ard-Iam, Noppadol, Rukyen, Pimprapa, Mahanonda, Rangsini, Kawkitinarong, Kamon, Auewarakul, Prasert, Utaisincharoen, Pongsak, Sirisinha, Stitaya, Mason, Carl J, Fukuda, Mark M, Pichyangkul, Sathit
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940995/
https://ncbi.nlm.nih.gov/pubmed/20627090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.07.017
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