Evaluation of In Vitro Cross-Reactivity to Avian H5N1 and Pandemic H1N1 2009 Influenza Following Prime Boost Regimens of Seasonal Influenza Vaccination in Healthy Human Subjects: A Randomised Trial

INTRODUCTION: Recent studies have demonstrated that inactivated seasonal influenza vaccines (IIV) may elicit production of heterosubtypic antibodies, which can neutralize avian H5N1 virus in a small proportion of subjects. We hypothesized that prime boost regimens of live and inactivated trivalent s...

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Main Authors: Bethell, Delia, Saunders, David, Jongkaewwattana, Anan, Kramyu, Jarin, Thitithayanont, Arunee, Wiboon-ut, Suwimon, Yongvanitchit, Kosol, Limsalakpetch, Amporn, Kum-Arb, Utaiwan, Uthaimongkol, Nichapat, Garcia, Jean Michel, Timmermans, Ans E., Peiris, Malik, Thomas, Stephen, Engering, Anneke, Jarman, Richard G., Mongkolsirichaikul, Duangrat, Mason, Carl, Khemnu, Nuanpan, Tyner, Stuart D., Fukuda, Mark M., Walsh, Douglas S., Pichyangkul, Sathit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608534/
https://ncbi.nlm.nih.gov/pubmed/23555741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059674
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