Evaluation of In Vitro Cross-Reactivity to Avian H5N1 and Pandemic H1N1 2009 Influenza Following Prime Boost Regimens of Seasonal Influenza Vaccination in Healthy Human Subjects: A Randomised Trial

INTRODUCTION: Recent studies have demonstrated that inactivated seasonal influenza vaccines (IIV) may elicit production of heterosubtypic antibodies, which can neutralize avian H5N1 virus in a small proportion of subjects. We hypothesized that prime boost regimens of live and inactivated trivalent s...

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Main Authors: Bethell, Delia, Saunders, David, Jongkaewwattana, Anan, Kramyu, Jarin, Thitithayanont, Arunee, Wiboon-ut, Suwimon, Yongvanitchit, Kosol, Limsalakpetch, Amporn, Kum-Arb, Utaiwan, Uthaimongkol, Nichapat, Garcia, Jean Michel, Timmermans, Ans E., Peiris, Malik, Thomas, Stephen, Engering, Anneke, Jarman, Richard G., Mongkolsirichaikul, Duangrat, Mason, Carl, Khemnu, Nuanpan, Tyner, Stuart D., Fukuda, Mark M., Walsh, Douglas S., Pichyangkul, Sathit
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608534/
https://ncbi.nlm.nih.gov/pubmed/23555741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059674
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