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ALPHAVIRUS REPLICON PARTICLES ACTING AS ADJUVANTS PROMOTE CD8(+) T CELL RESPONSES TO CO-DELIVERED ANTIGEN
Alphavirus replicon particles induce strong antibody and CD8(+) T cell responses to expressed antigens in numerous experimental systems. We have recently demonstrated that Venezuelan equine encephalitis virus replicon particles (VRP) possess adjuvant activity for systemic and mucosal antibody respon...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3608392/ https://ncbi.nlm.nih.gov/pubmed/18582997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.05.046 |
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