THE CONTRIBUTION OF TYPE I INTERFERON SIGNALING TO IMMUNITY INDUCED BY ALPHAVIRUS REPLICON VACCINES

The type I interferon (IFN) system is critical for protecting the mammalian host from numerous virus infections and plays a key role in shaping the anti-viral adaptive immune response. In this report, the importance of type I IFN signaling was assessed in a mouse model of alphavirus-induced humoral...

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Bibliographic Details
Main Authors: Thompson, Joseph M., Whitmore, Alan C., Staats, Herman F., Johnston, Robert
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595171/
https://ncbi.nlm.nih.gov/pubmed/18656518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.07.011
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